Results
Adoption of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers
On 28.Aug.2024, the Institute of Cellular Biology and Pathology "Nicolae Simionescu" received the Diploma of Excellence for Human Resources in Research from the European Commission.
Details here: https://www.icbp.ro/static/en/en-careers/otmr_strategy_hrs4r.html
Published papers
- Loredan S. Niculescu and Dimitris Kardassis, Chapter 8. Bridging the Gap in Transcriptomics: From Animal to Human Studies in Atherosclerosis, Book chapter in: Transcriptomics in Atherosclerosis: Deciphering Molecular Signatures and Advancing Therapeutic Strategies, Imprint: Elsevier, Editors: Yvan Devaux, Miron Sopić, Paperback ISBN: 9780443330643, eBook ISBN: 9780443330650, 2025.
- Dimitris Kardassis, Cécile Vindis, Camelia Sorina Stancu, Laura Toma, Anca Violeta Gafencu, Adriana Georgescu, Nicoleta Alexandru-Moise, Filippo Molica, Brenda R. Kwak, Alexandrina Burlacu, Ignacio Fernando Hall, Elena Butoi, Paolo Magni, Junxi Wu, Susana Novella, Luke F. Gamon, Michael J. Davies, Andrea Caporali, Fernando de la Cuesta, Tijana Mitić. Unravelling molecular mechanisms in atherosclerosis using cellular models and omics technologies. Vascular Pharmacology, Volume 158, 107452, 2025. doi: 10.1016/j.vph.2024.107452 (Q1-ranked).
- Laura Toma, Mariana Deleanu, Gabriela M. Sanda, Teodora Barbălată, Loredan S. Niculescu, Anca V. Sima, Camelia S. Stancu. Bioactive Compounds Formulated in Phytosomes Administered as Complementary Therapy for Metabolic Disorders. International Journal of Molecular Sciences 25(8): 4162, 2024. doi: 10.3390/ijms25084162 (Q1-ranked).
Communications at scientific meetings
International Conference: Molecular Biology - Current Aspects and Prospects, Cluj-Napoca, 4-7 November 2025
- Oral presentation: Jessica I.C. Ciobanu, Teodora Barbalata, Laura Toma, Elena V. Fuior, Madalina I. Fenyo, Anca V. Sima, Camelia S. Stancu.. CRISPR/dCas9 Long-Term Transcriptional Activation of Hepatic Alipoprotein A-I And Paraoxonase 1 to Improve HDL Function.
61st Annual Meeting of European Association for the Study of Diabetes (EASD), Wien, Austria, 15-19 September 2025
- Short oral presentation: Laura Toma, Teodora Barbălată, Jessica I.C. Ciobanu, Gabriela M. Sanda, Elena V. Fuior, Mădălina I. Fenyo, Loredan S. Niculescu, Anca V. Sima, Camelia S. Stancu. Transcriptional activation of endogenous paraoxonase 2 by CRISPR/dCas9 technology to improve the function of hepatocytes under pro-diabetic conditions; an in vitro and in vivo strategy.
Federation of European Biochemical Societies (FEBS) 2025 Congress, Istanbul, Turkey, 5-9 July 2025
- Poster communication: Teodora Barbălată, Oriana E. Moraru, Gabriela M. Sanda, Laura Toma, Camelia S. Stancu, Anca V. Sima, Loredan S. Niculescu. Circulating non-coding RNAs as promising biomarkers for atherosclerosis.
- Poster communication: Gabriela M. Sanda, Laura Toma, Jessica I.C. Ciobanu, Teodora Barbalata, Elena V. Fuior, Madalina I. Fenyo , Loredan S. Niculescu, Anca V. Sima, Camelia S. Stancu. Transcriptional activation of endogenous glutathione peroxidases by CRISPR/dCas9 technology to improve the antioxidant protection of enterocytes in vitro and in vivo.
Atherosclerosis - Gordon Research Conference "Genetics, Pathophysiology, and Translation", Castelldefels, Spania, 22 - 27 June 2025
- Poster communication: Laura Toma, Teodora Barbălată, Jessica I.C. Ciobanu, Gabriela M. Sanda, Elena V. Fuior, Madalina I. Fenyo, Loredan S. Niculescu, Anca V. Sima, Camelia S. Stancu. Transcriptional activation of endogenous apolipoprotein A-I and paraoxonase 1 by CRISPR/dCas9 technology to improve the function of high-density lipoproteins.
International Conference The 41st Annual Scientific Session of the Romanian Society for Cell Biology (RSCB), Targu Mures, Romania, 11-13 December 2024
- Oral communication in PhD students Session: Jessica I.C. Ciobanu, Laura Toma, Elena V. Fuior, Gabriela M. Sanda, Anca V. Sima, Camelia S. Stancu. CRISPR/dCas9 long-term transcriptional activation of hepatic key proteins to improve HDL function.
- Poster communication: Teodora Barbălată, Orina Moraru, Gabriela M. Sanda, Laura Toma, Camelia S. Stancu, Anca V. Sima, Loredan S. Niculescu. Non-coding RNAs as novel biomarkers in atherosclerosis.
The „XXXVII National Chemistry Conference CNCHIM 2024”, Târgoviște, Romania, 25-27 September 2024
- Poster communication: Mariana Deleanu, Laura Toma, Gabriela Sanda, Anca V. Sima, Justinian Tomescu, Georgeta Alexandru, Camelia S. Stancu. Preparation and characterization of hawthorn berries and grapes skin extracts; antioxidant and anti-inflammatory effects in endothelial cells.
Training stages performed by the team members
Dr. Raluca Tutuianu - 10-12 July 2023 - Summer School: Advancing skills in 3D skin and epidermal biology computer modelling of the COST action CA21108, University of Surrey, School of Chemistry and Chemical, Faculty of Engineering and Physical Sciences, Guildford, Surrey, UK
Dr. Raluca Tutuianu - 11-22 September 2023 - FELASA Accredited Course: 9th Laboratory Animal Science European Union Functions Course, Laboratory for Research of the Musculoskeletal System, School of Medicine, National & Kapodistrian Athens University, Greece
Drd. Daniela M. Ghetu - 1 September 2023 -31 May 2024 - Doctoral fellowship from Ministry of Education, H.G.118/2023 – 9-month stage and Medical Center of Leiden University, Anatomy and Embriology Department, Leiden, The Netherlands, Coordinator: dr. Karine Raymond
Dr. Teodora Barbălată and Drd. Jessica I.C. Ciobanu - 17 April -7 June 2024 - FELASA Accredited Course: 10th International Course „Care and use of laboratory animals: mice, rats and zebrafish”, Department of Biology, University of Crete and Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Crete, Greece
Drd. Daniela M. Ghetu – 28 June 2025 – 4 July 2025 - 3D Skin Models Training School COST CA21108 European Network for Skin Engineering and Modeling (NETSKINMODELS), Experimental Dermatology lab, Radboud University Medical Center, The Netherlands